This is a "point-and-click" adventure game based on the TV hospital drama House, M.D. Players can interview and examine patients, perform medical tests, solve puzzles, and investigate evidence to determine the appropriate action for each case. Some cases involve depictions of blood, including a victim of a car crash and a blood-stained towel. During patient interviews, the text references child abuse (e.g., "She hits me with a belt, most of the time" and "I don't want to say this, but . . . think her dad's abusing her?"), and questions related to sex or drugs (e.g., "Have you ever abused illegal drugs, like cocaine, crystal meth . . . ?" and "How many sex partners have you had in the last year?"). Additionally, the dialogue contains lines about masturbation, "sex with Willy Wonka," and being on an "all-heroin diet." The words "b*tch," "bastard," and "a*s" also appear in dialogue.