This is an action-adventure game in which players assume the role of four Spider-Man in four distinct settings and dimensions: Noir, Amazing, 2099, and Ultimate. Players embark on a quest to collect mystical fragments across dimensions, while engaging in frequent hand-to-hand combat. Players punch, kick, and use web-based weapons to defeat an assortment of enemies (gun-wielding thugs, robots, symbiotic creatures, futuristic law enforcement, etc.).Boss battles include slow-motion effects and extended combat in which players pummel villains with punches from a first-person perspective. Dialogue contains the words "b*tch" and "bastard" and phrases/words such as "Pervert," "Touch me! Touch me! Go on, no one's lookin'" and "that's kind of, like creepy . . . I'd still hit it though."